Contraception for Men: A Breakthrough New Approach
نویسنده
چکیده
There has not been a new reversible contraceptive for men since the development of the condom, centuries ago. Matzuk et al. describe a new molecular approach using administration of a small molecule to directly and reversibly inhibit spermatogenesis in mice by blocking the function of a testicular bromodomain without apparent adverse effect on the organism or offspring.
منابع مشابه
[Male contraception].
Clear evidence shows that many men and women would welcome new male methods of contraception, but none have become available. The hormonal approach is based on suppression of gonadotropins and thus of testicular function and spermatogenesis, and has been investigated for several decades. This approach can achieve sufficient suppression of spermatogenesis for effective contraception in most men,...
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عنوان ژورنال:
- Cell
دوره 150 شماره
صفحات -
تاریخ انتشار 2012